Found 15 matching trials
Pilot Study of [68Ga]Ga-ABY-025 Imaging in Patients Undergoing Treatment With HER2-targeted Therapy
EARLY_PHASE1The purpose of this study is to determine if the radiotracer, \[68Ga\]Ga-AB...
Location
Vanderbilt University Medical Center
Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer
PHASE1This phase Ib/II trial studies the side effects and best dose of ribociclib...
Status
Active Not Recruiting
Location
UCLA / Jonsson Comprehensive Cancer Center
Neoadjuvant Trastuzumab, Pertuzumab and Tucatinib Without Chemotherapy in HER2-positive Breast Cancer: the TRAIN-4 Study
PHASE1This is a single-center, phase 1b study evaluating the safety and feasibili...
Location
Netherlands Cancer Institute
Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)
PHASE2Cancer drugs which target the effects of abnormal gene changes are called '...
Location
Cross Cancer Institute
Treatment With Tucatinib in Patients With an Isolated Brain Progression of a Metastatic Breast Cancer
PHASE2The overall survival of patients with metastatic breast cancer has steadily...
Status
Active Not Recruiting
Location
Institut de Cancérologie de l'Ouest - Site Paul Papin
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
PHASE2The purpose of this study is to further advance the ability to practice per...
Location
University of Alabama at Birmingham
A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer
PHASE1DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour...
Status
Active Not Recruiting
TKIs vs. Pertuzumab in HER2+ Breast Cancer Patients With Active Brain Metastases (HER2BRAIN)
PHASE2This is a prospective, randomized, 2-arm, Phrase 2, superiority and multice...
Location
Peking University International Hospital
The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer
PHASE2The purpose of this study is to test the safety and effectiveness of a sequ...
Location
Dana-Farber Cancer Institute
A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer
PHASE3This study is being done to see if tucatinib works better than placebo when...
Status
Active Not Recruiting
Location
Mayo Clinic Hospital